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Pathogenic Nocardia cyriacigeorgica and Nocardia nova Evolve To Resist Trimethoprim-Sulfamethoxazole by both Expected and Unexpected Pathways

Nocardia spp. are Gram-positive opportunistic pathogens that affect largely immunocompromised patients, leading to serious pulmonary or systemic infections. Combination therapy using the folate biosynthesis pathway inhibitors trimethoprim (TMP) and sulfamethoxazole (SMX) is commonly used as an antim...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Mehta, H., Weng, J., Prater, A., Elworth, R. A. L., Han, X., Shamoo, Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021631/
https://ncbi.nlm.nih.gov/pubmed/29686152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00364-18
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