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Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)(+)-Dependent Malic Enzyme

Human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-N...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Hsieh, Ju-Yi, Shih, Wan-Ting, Kuo, Yu-Hsuan, Liu, Guang-Yaw, Hung, Hui-Chih
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591397/
https://ncbi.nlm.nih.gov/pubmed/31235710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45282-0
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