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Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)(+)-Dependent Malic Enzyme

Human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME) has a dimer of dimers quaternary structure with two independent allosteric sites in each monomer. Here, we reveal the different effects of nucleotide ligands on the quaternary structure regulation and functional role of the human m-N...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Hsieh, Ju-Yi, Shih, Wan-Ting, Kuo, Yu-Hsuan, Liu, Guang-Yaw, Hung, Hui-Chih
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591397/
https://ncbi.nlm.nih.gov/pubmed/31235710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45282-0
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