Recombinant production of human α(2)-macroglobulin variants and interaction studies with recombinant G-related α(2)-macroglobulin binding protein and latent transforming growth factor-β(2)

α(2)-Macroglobulins (α(2)Ms) regulate peptidases, hormones and cytokines. Mediated by peptidase cleavage, they transit between native, intact forms and activated, induced forms. α(2)Ms have been studied over decades using authentic material from primary sources, which was limited by sample heterogen...

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Vydáno v:Sci Rep
Hlavní autoři: Marino-Puertas, Laura, del Amo-Maestro, Laura, Taulés, Marta, Gomis-Rüth, F. Xavier, Goulas, Theodoros
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591361/
https://ncbi.nlm.nih.gov/pubmed/31235767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45712-z
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