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Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions
Diverse antibody repertoires are generated through remote genomic interactions involving immunoglobulin variable (V(H)), diversity (D(H)) and joining (J(H)) gene segments. How such interactions are orchestrated remains unknown. Here we develop a strategy to track V(H)-D(H)J(H) motion in B-lymphocyte...
Gorde:
Argitaratua izan da: | Nat Commun |
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Egile Nagusiak: | , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Nature Publishing Group UK
2019
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591236/ https://ncbi.nlm.nih.gov/pubmed/31235807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10628-9 |
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