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Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions
Diverse antibody repertoires are generated through remote genomic interactions involving immunoglobulin variable (V(H)), diversity (D(H)) and joining (J(H)) gene segments. How such interactions are orchestrated remains unknown. Here we develop a strategy to track V(H)-D(H)J(H) motion in B-lymphocyte...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591236/ https://ncbi.nlm.nih.gov/pubmed/31235807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10628-9 |
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