3D-Trajectories Adopted by Coding and Regulatory DNA Elements: First-Passage Times for Genomic Interactions

During B lymphocyte development, immunoglobulin heavy chain variable (V(H)), diversity (D(H)) and joining (J(H)) segments assemble to generate a diverse antigen receptor repertoire. Here we have marked the distal V(H) and D(H)-J(H)-Eμ regions with Tet-operator binding sites and traced their 3D-traje...

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Bibliographic Details
Main Authors: Lucas, Joseph S., Zhang, Yaojun, Dudko, Olga K., Murre, Cornelis
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113018/
https://ncbi.nlm.nih.gov/pubmed/24998931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.036
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