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3D-Trajectories Adopted by Coding and Regulatory DNA Elements: First-Passage Times for Genomic Interactions
During B lymphocyte development, immunoglobulin heavy chain variable (V(H)), diversity (D(H)) and joining (J(H)) segments assemble to generate a diverse antigen receptor repertoire. Here we have marked the distal V(H) and D(H)-J(H)-Eμ regions with Tet-operator binding sites and traced their 3D-traje...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113018/ https://ncbi.nlm.nih.gov/pubmed/24998931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.036 |
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