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CARBOHYDRATE ANTIGEN EXPRESSION AND ANTI-PIG ANTIBODIES IN NEW WORLD CAPUCHIN MONKEYS: RELEVANCE TO STUDIES OF XENOTRANSPLANTATION

BACKGROUND: Old World nonhuman primates (OWNHPs) are used for preclinical pig-to-NHP studies. However, like pigs, OWNHPs express Neu5Gc, and therefore do not develop natural anti-Neu5Gc antibodies. New World NHPs (NWNHPs) have been reported not to express Neu5Gc. We investigated the potential of NWN...

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Detalhes bibliográficos
Publicado no:Xenotransplantation
Main Authors: LI, QI, Shaikh, Sahar, Iwase, Hayato, Long, Cassandra, Lee, Whayoung, ZHANG, ZHONGQIANG, Wang, Yi, Ayares, David, COOPER, DAVID K.C., HARA, HIDETAKA
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591082/
https://ncbi.nlm.nih.gov/pubmed/30770572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12498
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