Incretin dysfunction and hyperglycemia in cystic fibrosis: role of acyl-ghrelin

BACKGROUND: Insulin secretion is insufficient in cystic fibrosis (CF), even before diabetes is present, though the mechanisms involved remain unclear. Acyl-ghrelin (AG) can diminish insulin secretion and is elevated in humans with CF. METHODS: We tested the hypothesis that elevated AG contributes to...

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Bibliografiske detaljer
Udgivet i:J Cyst Fibros
Main Authors: Sun, Xingshen, Yi, Yaling, Liang, Bo, Yang, Yu, He, Nan, Ode, Katie Larson, Uc, Aliye, Wang, Kai, Gibson-Corley, Katherine N., Engelhardt, John F., Norris, Andrew W.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591024/
https://ncbi.nlm.nih.gov/pubmed/30738804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2019.01.010
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