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Genome plasticity in Candida albicans is driven by long repeat sequences

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...

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Vydáno v:eLife
Hlavní autoři: Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591007/
https://ncbi.nlm.nih.gov/pubmed/31172944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45954
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