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Genome plasticity in Candida albicans is driven by long repeat sequences

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...

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Pubblicato in:eLife
Autori principali: Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591007/
https://ncbi.nlm.nih.gov/pubmed/31172944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45954
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