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Genome plasticity in Candida albicans is driven by long repeat sequences

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591007/
https://ncbi.nlm.nih.gov/pubmed/31172944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45954
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