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Genome plasticity in Candida albicans is driven by long repeat sequences

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen Candida albicans, CNV and LOH confer increased viru...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Todd, Robert T, Wikoff, Tyler D, Forche, Anja, Selmecki, Anna
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591007/
https://ncbi.nlm.nih.gov/pubmed/31172944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45954
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