Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment

Inhibitors of the 20S proteasome such as bortezomib are cytotoxic to tumor cells and have been proven to be valuable for the clinical management of multiple myeloma. The therapeutic efficacy of bortezomib is, however, hampered by the emergence of acquired resistance. Available data suggest that bloc...

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Bibliografiska uppgifter
I publikationen:Oxid Med Cell Longev
Huvudupphovsmän: Zhang, Xiaonan, Espinosa, Belén, Saei, Amir Ata, D'Arcy, Padraig, Zubarev, Roman A., Linder, Stig
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590552/
https://ncbi.nlm.nih.gov/pubmed/31281566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1659468
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