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Desensitization of cAMP Accumulation via Human β3-Adrenoceptors Expressed in Human Embryonic Kidney Cells by Full, Partial, and Biased Agonists
β(3)-Adrenoceptors couple not only to cAMP formation but, at least in some cell types, also to alternative signaling pathways such as phosphorylation of extracellular signal-regulated kinase (ERK). β(3)-Adrenoceptor agonists are used in long-term symptomatic treatment of the overactive bladder syndr...
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| Publié dans: | Front Pharmacol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590479/ https://ncbi.nlm.nih.gov/pubmed/31263412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00596 |
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