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Phospholipase C (PLC)ɛ Promotes Androgen Receptor Antagonist Resistance via the Bone Morphogenetic Protein (BMP)-6/SMAD Axis in a Castration-Resistant Prostate Cancer Cell Line
BACKGROUND: Primary therapy for patients with advanced prostate cancer (PCa) consists of androgen deprivation therapy targeting the androgen receptor (AR) axis. However, most tumors progress to castration-resistant prostate cancer (CRPC) within 18–24 months. The purpose of the present study was to i...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Med Sci Monit |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
International Scientific Literature, Inc.
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590100/ https://ncbi.nlm.nih.gov/pubmed/31201297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915828 |
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