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Combination of phospholipase Cε knockdown with GANT61 sensitizes castration-resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway

Castration-resistant prostate cancer (CRPC) is a major challenge in the treatment of prostate cancer (PCa). Phospholipase Cε (PLCε), an oncogene, has been found to be involved in the carcinogenesis, tumor proliferation and migration of several types of cancer. The effects, however, of PLCε on CRPC r...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Sun, Wei, Li, Luo, Du, Zhongbo, Quan, Zhen, Yuan, Mengjuan, Cheng, Honglin, Gao, Yingying, Luo, Chunli, Wu, Xiaohou
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448124/
https://ncbi.nlm.nih.gov/pubmed/30864728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7054
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