Combination of phospholipase Cε knockdown with GANT61 sensitizes castration-resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway

Castration-resistant prostate cancer (CRPC) is a major challenge in the treatment of prostate cancer (PCa). Phospholipase Cε (PLCε), an oncogene, has been found to be involved in the carcinogenesis, tumor proliferation and migration of several types of cancer. The effects, however, of PLCε on CRPC r...

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Vydáno v:Oncol Rep
Hlavní autoři: Sun, Wei, Li, Luo, Du, Zhongbo, Quan, Zhen, Yuan, Mengjuan, Cheng, Honglin, Gao, Yingying, Luo, Chunli, Wu, Xiaohou
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448124/
https://ncbi.nlm.nih.gov/pubmed/30864728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7054
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