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Hypomethylating agent alters the immune microenvironment in AML and enhances the immunogenicity of a DC/AML vaccine
Acute myeloid leukemia (AML) is a lethal hematologic malignancy characterized by an immunosuppressive milieu in the tumor microenvironment (TME) that fosters disease growth and therapeutic resistance. Hypomethylating agents (HMAs) demonstrate clinical efficacy in AML patients and exert immunomodulat...
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| Gepubliceerd in: | Br J Haematol |
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590084/ https://ncbi.nlm.nih.gov/pubmed/30828801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.15818 |
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