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How Does an Anti-CTLA4 Antibody Promote Cancer Immunity?

Anti-CTLA-4 antibodies can induce lasting protection for some melanoma patients. However, their therapeutic potential is limited by significant immunotherapy-related adverse effects (irAE). Here, we argue that the therapeutic effect may be based on an agonist activity that is fundamentally distinct,...

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Detalles Bibliográficos
Publicado en:Trends Immunol
Main Authors: Liu, Yang, Zheng, Pan
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589807/
https://ncbi.nlm.nih.gov/pubmed/30497614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2018.10.009
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