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Preserving the CTLA-4 checkpoint for safer and more effective cancer immunotherapy
A major paradigm in cancer immunotherapy is to use checkpoint inhibitors to break regulatory mechanisms that usually guard the host against autoimmune diseases. CTLA-4-targeting immunotherapy was the first example that help to establish this paradigm. However, the clinically tested anti-CTLA-4 antib...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7210725/ https://ncbi.nlm.nih.gov/pubmed/31836191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.11.003 |
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