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Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin
Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein develop a blood-lymphatic mixing phenotype. We investig...
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| Udgivet i: | Platelets |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589745/ https://ncbi.nlm.nih.gov/pubmed/28727496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2017.1336210 |
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