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The physiological and pathophysiological roles of platelet CLEC-2

CLEC-2 is a C-type lectin receptor which is highly expressed on platelets but also found at low levels on different immune cells. CLEC-2 elicits powerful platelet activation upon engagement by its endogenous ligand, the mucin-type glycoprotein podoplanin. Podoplanin is expressed in a variety of tiss...

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Detalhes bibliográficos
Main Authors: Navarro-Núñez, Leyre, Langan, Stacey A, Nash, Gerard B, Watson, Steve P
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693086/
https://ncbi.nlm.nih.gov/pubmed/23572154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH13-01-0060
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