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Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation

Junctional adhesion molecule-A (JAM-A), an epithelial tight junction protein, plays an important role in regulating intestinal permeability through association with a scaffold signaling complex containing ZO-2, Afadin, and the small GTPase Rap2. Under inflammatory conditions, we report that the cyto...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Fan, Shuling, Weight, Caroline M., Luissint, Anny-Claude, Hilgarth, Roland S., Brazil, Jennifer C., Ettel, Mark, Nusrat, Asma, Parkos, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589701/
https://ncbi.nlm.nih.gov/pubmed/30625033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-08-0531
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