Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo

CD47 is a ubiquitously expressed transmembrane glycoprotein that regulates inflammatory responses and tissue repair. Here, we show that normal mice treated with anti-CD47 antibodies, and Cd47-null mice have impaired intestinal mucosal wound healing. Furthermore, intestinal epithelial cell (IEC)-spec...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Reed, Michelle, Luissint, Anny-Claude, Azcutia, Veronica, Fan, Shuling, O’Leary, Monique N., Quiros, Miguel, Brazil, Jennifer, Nusrat, Asma, Parkos, Charles A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825175/
https://ncbi.nlm.nih.gov/pubmed/31676794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12968-y
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