Preformed chromatin topology assists transcriptional robustness of Shh during limb development

Long-range gene regulation involves physical proximity between enhancers and promoters to generate precise patterns of gene expression in space and time. However, in some cases, proximity coincides with gene activation, whereas, in others, preformed topologies already exist before activation. In thi...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Paliou, Christina, Guckelberger, Philine, Schöpflin, Robert, Heinrich, Verena, Esposito, Andrea, Chiariello, Andrea M., Bianco, Simona, Annunziatella, Carlo, Helmuth, Johannes, Haas, Stefan, Jerković, Ivana, Brieske, Norbert, Wittler, Lars, Timmermann, Bernd, Nicodemi, Mario, Vingron, Martin, Mundlos, Stefan, Andrey, Guillaume
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589666/
https://ncbi.nlm.nih.gov/pubmed/31147463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900672116
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