Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics

Missense mutations K15N and R21H in striated muscle tropomyosin are linked to dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), respectively. Tropomyosin, together with the troponin complex, regulates muscle contraction and, along with tropomodulin and leiomodin, controls the unifo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Ly, Thu, Pappas, Christopher T., Johnson, Dylan, Schlecht, William, Colpan, Mert, Galkin, Vitold E., Gregorio, Carol C., Dong, Wen-Ji, Kostyukova, Alla S.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2019
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589558/
https://ncbi.nlm.nih.gov/pubmed/30462572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0406
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker