Loss of VGLL4 suppresses tumor PD‐L1 expression and immune evasion

Targeting immune checkpoints, such as PD‐L1 and its receptor PD‐1, has opened a new avenue for treating cancers. Understanding the regulatory mechanism of PD‐L1 and PD‐1 will improve the clinical response rate and efficacy of PD‐1/PD‐L1 blockade in cancer patients and the development of combinatoria...

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Vydáno v:EMBO J
Hlavní autoři: Wu, Ailing, Wu, Qingzhe, Deng, Yujie, Liu, Yuning, Lu, Jinqiu, Liu, Liansheng, Li, Xiaoling, Liao, Cheng, Zhao, Bin, Song, Hai
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589543/
https://ncbi.nlm.nih.gov/pubmed/30396996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899506
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