Purification of glycosylphosphatidylinositol-anchored mucins from Trypanosoma cruzi trypomastigotes and synthesis of α-Gal-containing neoglycoproteins: application as biomarkers for reliable diagnosis and early assessment of chemotherapeutic outcomes of Chagas disease

Chagas disease (ChD), caused by the protozoan parasite Trypanosoma cruzi, affects millions of people worldwide. Chemotherapy is restricted to two drugs, which are partially effective and may cause severe side effects, leading to cessation of treatment in a significant number of patients. Currently,...

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Publicado no:Methods Mol Biol
Main Authors: Ortega-Rodriguez, Uriel, Portillo, Susana, Ashmus, Roger A., Duran, Jerry A., Schocker, Nathaniel S., Iniguez, Eva, Montoya, Alba L., Zepeda, Brenda G., Olivas, Janet J., Karimi, Nasim H., Alonso-Padilla, Julio, Izquierdo, Luis, Pinazo, Maria-Jesús, de Noya, Belkisyolé Alarcón, Noya, Oscar, Maldonado, Rosa A., Torrico, Faustino, Gascón, Joaquim, Michael, Katja, Almeida, Igor C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589430/
https://ncbi.nlm.nih.gov/pubmed/30868536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9148-8_22
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