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Sequencing abasic sites in DNA at single-nucleotide resolution
In DNA, the loss of a nucleobase by hydrolysis generates an abasic site. Formed as a result of DNA damage, as well as a key intermediate during the base excision repair pathway, abasic sites are frequent DNA lesions which can lead to mutations and strand breaks. Here we present snAP-seq, a chemical...
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| Publicado no: | Nat Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589398/ https://ncbi.nlm.nih.gov/pubmed/31209299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0279-9 |
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