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Lipid-Modulation of Membrane Insertion and Refolding of the Apoptotic Inhibitor Bcl-xL
Bcl-xL is a member of the Bcl-2 family of apoptotic regulators, responsible for inhibiting the permeabilization of the mitochondrial outer membrane, and a promising anti-cancer target. Bcl-xL exists in the following conformations, each believed to play a role in the inhibition of apoptosis: (a) a so...
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| Pubblicato in: | Biochim Biophys Acta Proteins Proteom |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589348/ https://ncbi.nlm.nih.gov/pubmed/31004798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2019.04.006 |
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