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Lipid-Modulation of Membrane Insertion and Refolding of the Apoptotic Inhibitor Bcl-xL

Bcl-xL is a member of the Bcl-2 family of apoptotic regulators, responsible for inhibiting the permeabilization of the mitochondrial outer membrane, and a promising anti-cancer target. Bcl-xL exists in the following conformations, each believed to play a role in the inhibition of apoptosis: (a) a so...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Proteins Proteom
Main Authors: Vasquez-Montes, Victor, Vargas-Uribe, Mauricio, Pandey, Nitin K., Rodnin, Mykola V., Langen, Ralf, Ladokhin, Alexey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589348/
https://ncbi.nlm.nih.gov/pubmed/31004798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2019.04.006
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