Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice

OBJECTIVE: Renal tubular injury is an early characteristic of diabetic nephropathy (DN) that is related to mitochondrial dysfunction. In this study, we explore the effects and mechanisms of mitochondria-targeted peptide SS31 on renal tubulointerstitial injury in DN. METHOD: 40 C57BL/6 mice were rand...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Yang, Shi-kun, Li, Ai-mei, Han, Ya-chun, Peng, Can-hui, Song, Na, Yang, Ming, Zhan, Ming, Zeng, Ling-feng, Song, Pan-ai, Zhang, Wei, Tang, Shi-qi, Zhang, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589270/
https://ncbi.nlm.nih.gov/pubmed/31281569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2346580
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