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Matrix-bound AGEs enhance TGFβ2-mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation

Advanced glycation end products (AGEs) are post-translational modifications formed from the reaction of reactive carbonyl compounds with amino groups in proteins. Our laboratory has previously shown that AGEs in extracellular matrix (ECM) proteins promote TGFβ2 (transforming growth factor-beta 2)-me...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Nam, Mi-Hyun, Nagaraj, Ram H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589163/
https://ncbi.nlm.nih.gov/pubmed/29588342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170856
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