Aspirin Inhibits TGFβ2-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells: Selective acetylation of K56 and K122 in histone H3

Posterior capsule opacification (PCO) is a complication after cataract surgery that can disrupt vision. The epithelial to mesenchymal transition (EMT) of lens epithelial cells (LECs) in response to transforming growth factor β2 (TGFβ2) has been considered an obligatory mechanism for PCO. In this stu...

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Pubblicato in:Biochem J
Autori principali: Nam, Mi-Hyun, Smith, Andrew J.O., Pantcheva, Mina B., Park, Ko Uoon, Brzezinski, Joseph A., Galligan, James J., Fritz, Kristofer, Wormstone, I. Michael, Nagaraj, Ram H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259308/
https://ncbi.nlm.nih.gov/pubmed/31815277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190540
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