Nonhelical Helicobacter pylori Mutants Show Altered Gland Colonization and Elicit Less Gastric Pathology than Helical Bacteria during Chronic Infection

Half of all humans harbor Helicobacter pylori in their stomachs. Helical cell shape is thought to facilitate H. pylori’s ability to bore into the protective mucus layer in a corkscrew-like motion, thereby enhancing colonization of the stomach. H. pylori cell shape mutants show impaired colonization...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Martínez, Laura E., O’Brien, Valerie P., Leverich, Christina K., Knoblaugh, Sue E., Salama, Nina R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589060/
https://ncbi.nlm.nih.gov/pubmed/31061142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00904-18
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