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Nonhelical Helicobacter pylori Mutants Show Altered Gland Colonization and Elicit Less Gastric Pathology than Helical Bacteria during Chronic Infection

Half of all humans harbor Helicobacter pylori in their stomachs. Helical cell shape is thought to facilitate H. pylori’s ability to bore into the protective mucus layer in a corkscrew-like motion, thereby enhancing colonization of the stomach. H. pylori cell shape mutants show impaired colonization...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Martínez, Laura E., O’Brien, Valerie P., Leverich, Christina K., Knoblaugh, Sue E., Salama, Nina R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589060/
https://ncbi.nlm.nih.gov/pubmed/31061142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00904-18
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