Sustained Helicobacter pylori infection accelerates gastric dysplasia in a mouse model

More than 80% of gastric cancer is attributable to stomach infection with Helicobacter pylori (Hp). Gastric preneoplastic progression involves sequential tissue changes, including loss of parietal cells, metaplasia and dysplasia. In transgenic mice, active KRAS expression recapitulates these tissue...

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Bibliographic Details
Published in:Life Sci Alliance
Main Authors: O’Brien, Valerie P, Koehne, Amanda L, Dubrulle, Julien, Rodriguez, Armando E, Leverich, Christina K, Kong, V Paul, Campbell, Jean S, Pierce, Robert H, Goldenring, James R, Choi, Eunyoung, Salama, Nina R
Format: Artigo
Language:Inglês
Published: Life Science Alliance LLC 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768197/
https://ncbi.nlm.nih.gov/pubmed/33310760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000967
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