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The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time

The initial binding of tropomyosin onto actin filaments and then its polymerization into continuous cables on the filament surface must be precisely tuned to overall thin-filament structure, function, and performance. Low-affinity interaction of tropomyosin with actin has to be sufficiently strong t...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Lehman, William, Moore, Jeffrey R., Campbell, Stuart G., Rynkiewicz, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588729/
https://ncbi.nlm.nih.gov/pubmed/31130236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.05.009
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