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Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data

Understanding the clonal architecture and evolutionary history of a tumour poses one of the key challenges to overcome treatment failure due to resistant cell populations. Previously, studies on subclonal tumour evolution have been primarily based on bulk sequencing and in some recent cases on singl...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Malikic, Salem, Jahn, Katharina, Kuipers, Jack, Sahinalp, S. Cenk, Beerenwinkel, Niko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588593/
https://ncbi.nlm.nih.gov/pubmed/31227714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10737-5
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