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Role of PTA in the prevention of Cu(Amyloid-β) induced ROS formation and Amyloid-β oligomerisation in the presence of Zn

Metal-targeting drugs are being widely explored as a possible treatment of Alzheimer’s disease, but most of these ligands are developed to coordinate Cu(II). In a previous communication (Metallomics, 2015, 7, 1229) we have shown another strategy where Cu(I) was targeted with the PTA (1,3,5-triaza-7-...

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Dettagli Bibliografici
Pubblicato in:Metallomics
Autori principali: Atrián-Blasco, Elena, Cerrada, Elena, Faller, Peter, Laguna, Mariano, Hureau, Christelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588526/
https://ncbi.nlm.nih.gov/pubmed/31098605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9mt00011a
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