ロード中...
Drugging the Folate Pathway in Mycobacterium Tuberculosis: The Role of Multi-Targeting Agents
The folate biosynthetic pathway offers many druggable targets that have yet to be exploited in TB therapy. Herein, we have identified a series of small molecules that interrupt Mycobacterium tuberculosis folate metabolism by dual targeting of dihydrofolate reductase (DHFR), a key enzyme in the folat...
保存先:
| 出版年: | Cell Chem Biol |
|---|---|
| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588435/ https://ncbi.nlm.nih.gov/pubmed/30930162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.02.013 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|