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In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis

The in vitro activity of contezolid (MRX-I) against clinical isolates of Mycobacterium tuberculosis was evaluated using a microtiter broth dilution assay. MRX-I was as effective as linezolid (LZD) in vitro. MRX-I and LZD were subsequently studied in BALB/c mice infected intranasally with M. tubercul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Shoen, Carolyn, DeStefano, Michelle, Hafkin, Barry, Cynamon, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105800/
https://ncbi.nlm.nih.gov/pubmed/29784848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00493-18
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