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EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis

Epstein–Barr virus (EBV) is a ubiquitous oncogenic virus that induces many cancers. N6-Methyladenosine (m6A) modification regulates many cellular processes. We explored the role of m6A in EBV gene regulation and associated cancers. We have comprehensively defined m6A modification of EBV latent and l...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Lang, Fengchao, Singh, Rajnish Kumar, Pei, Yonggang, Zhang, Shengwei, Sun, Kunfeng, Robertson, Erle S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588254/
https://ncbi.nlm.nih.gov/pubmed/31226160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007796
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