Mettl14 is essential for epitranscriptomic regulation of striatal function and learning

N(6)-methyladenosine (m(6)A) regulates mRNA metabolism and translation, serving as an important source of post-transcriptional regulation. To date, the functional consequences of m(6)A deficiency within the adult brain have not been determined. To achieve m(6)A deficiency, we deleted Mettl14, an ess...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Koranda, Jessica L., Dore, Lou, Shi, Hailing, Patel, Meera J., Vaasjo, Lee O., Rao, Meghana N., Chen, Kai, Lu, Zhike, Yi, Yangtian, Chi, Wanhao, He, Chuan, Zhuang, Xiaoxi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082022/
https://ncbi.nlm.nih.gov/pubmed/30056831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.06.007
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