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Prevention of allergy by virus‐like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model

BACKGROUND: In high‐risk populations, allergen‐specific prophylaxis could protect from sensitization and subsequent development of allergic disease. However, such treatment might itself induce sensitization and allergies, thus requiring hypoallergenic vaccine formulations. We here characterized the...

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Bibliographic Details
Published in:Allergy
Main Authors: Kratzer, Bernhard, Köhler, Cordula, Hofer, Sandra, Smole, Ursula, Trapin, Doris, Iturri, Jagoba, Pum, Dietmar, Kienzl, Philip, Elbe‐Bürger, Adelheid, Gattinger, Pia, Mittermann, Irene, Linhart, Birgit, Gadermaier, Gabriele, Jahn‐Schmid, Beatrice, Neunkirchner, Alina, Valenta, Rudolf, Pickl, Winfried F.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587790/
https://ncbi.nlm.nih.gov/pubmed/30035810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13573
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