Allergen alters IL‐2/αIL‐2‐based Treg expansion but not tolerance induction in an allergen‐specific mouse model

BACKGROUND: Regulatory T lymphocytes (Treg) play an important role in preventing allergic diseases. We characterized Treg expansion kinetics, marker profiles, and recirculation behavior in allergen‐challenged mice, which had been pretreated with IL‐2/αIL‐2 complexes in the presence or absence of all...

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Bibliographic Details
Published in:Allergy
Main Authors: Köhler, Cordula, Smole, Ursula, Kratzer, Bernhard, Trapin, Doris, Schmetterer, Klaus G., Pickl, Winfried F.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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ORIGINAL ARTICLES
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383865/
https://ncbi.nlm.nih.gov/pubmed/31991489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14203
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