Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Aggressive tumor cells can adopt an endothelial cell‐like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis. This adoptive mechanism is referred to as vascular mimicry and it is associated with poor survival in cancer patients. To what extent tumor c...

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Veröffentlicht in:J Pathol
Hauptverfasser: Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak‐Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan‐Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl‐Henrik, Cao, Yihai, Griffioen, Arjan W
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2018
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Original Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587443/
https://ncbi.nlm.nih.gov/pubmed/30101525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5152
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