Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Aggressive tumor cells can adopt an endothelial cell‐like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis. This adoptive mechanism is referred to as vascular mimicry and it is associated with poor survival in cancer patients. To what extent tumor c...

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Vydáno v:J Pathol
Hlavní autoři: Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak‐Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan‐Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl‐Henrik, Cao, Yihai, Griffioen, Arjan W
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2018
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587443/
https://ncbi.nlm.nih.gov/pubmed/30101525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5152
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