Artesunate, an Anti-Malaria Agent, Attenuates Experimental Osteoarthritis by Inhibiting Bone Resorption and CD31(hi)Emcn(hi) Vessel Formation in Subchondral Bone

Osteoarthritis (OA) is a common and debilitating joint disease worldwide without interventions available to reverse its progression. Artesunate (ART), an anti-malaria agent, possesses diverse biological activities, including the inhibition of osteoclastogenesis and angiogenesis in various cells, but...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Yicheng, Mu, Wenbo, Xu, Boyong, Ren, Jiangdong, Wahafu, Tuerhongjiang, Wuermanbieke, Shalitanati, Ma, Hairong, Gao, Hongwei, Liu, Yang, Zhang, Keyuan, Amat, Abdusami, Cao, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587439/
https://ncbi.nlm.nih.gov/pubmed/31258481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00685
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