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Histone Deacetylase Inhibitors Reduce Cysts by Activating Autophagy in Polycystic Kidney Disease
BACKGROUND: Histone deacetylase inhibitors (HDACi) have therapeutic effects on various models of renal diseases including autosomal dominant polycystic kidney disease (ADPKD), but the molecular mechanism is unclear. OBJECTIVES: Here, we studied the role of trichostatin A (TSA), a specific HDACi, in...
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| Publicado no: | Kidney Dis (Basel) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587212/ https://ncbi.nlm.nih.gov/pubmed/31259178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499368 |
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