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The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms

Addiction is a disease in which, after a period of recreational use, a subset of individuals develops compulsive use that does not stop even in light of major negative consequences. Here, we review the evidence for underlying epigenetic remodeling in brain in two settings. First, excessive dopamine...

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Publicado en:Neuron
Autores principales: Nestler, Eric J., Lüscher, Christian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587180/
https://ncbi.nlm.nih.gov/pubmed/30946825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.01.016
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